Adenovirus-mediated delivery of bFGF small interfering RNA increases levels of connexin 43 in the glioma cell line, U251
Abstract Background bFGF is an important growth factor for glioma cell proliferation and invasion, while connexin 43 is implicated in the suppression of glioma growth.Correspondingly, gliomas have been shown to have reduced, or compromised, connexin 43 expression.Methods In this study, a bFGF-targeted siRNA was delivered to the glioma cell line, U2